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Established Level A · strong human evidence

Magnesium

Foundational nutrition

Mechanism

A cofactor of hundreds of reactions, including those that produce ATP.

Research summary

Correcting a deficit makes nutritional sense. Supplementing without a deficit is not an anti-aging strategy.

Human evidence

Established as an essential nutrient. It is not a treatment for aging.

Safety

This is not a treatment. Anyone who is pregnant, nursing, underage, or taking medication should consult a professional before using a supplement. Too much can cause diarrhea, and kidney disease calls for caution.

References

1. Hallmarks of aging: An expanding universeLópez-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. Cell, 2023.DOI 10.1016/j.cell.2022.11.001Updates the framework to twelve hallmarks, including chronic inflammation and dysbiosis. It does not show that human aging can be slowed.

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