Conceptual illustration of neurons and blue light, made for this site. Not a photograph of an experiment and not a figure from a paper.

NOBEL PRIZE 2026

GLOBAL LONGEVITY FRONTIERS

China, Japan, the United States and Europe. A card is a checked source, not a promise that aging can be stopped.

Conceptual illustration of neurons and blue light, made for this site. Not a photograph of an experiment and not a figure from a paper.

Conceptual illustration made for this site. Not a photograph of an experiment and not a figure from a paper.

China · Animal study

Senescence-resistant cells and FOXO3

Cell, 2025. Lei, Liu and colleagues · 2025-06-13

Lei and colleagues, Cell, 2025, describe human mesenchymal progenitor cells edited at FOXO3 and given intravenously to aged macaques for 44 weeks. It is a non-human primate study, not a human trial and not an approved treatment. Nature Aging later published a highlight of that work. It does not show that human aging is slowed.

Sources

https://doi.org/10.1038/s43587-025-00930-1

Conceptual illustration made for this site. Not a photograph of an experiment and not a figure from a paper.

China · Scientific perspective

The X-Age Project: a plan for Chinese aging clocks

Aging Biomarker Consortium · 2025

Li and colleagues, Nature Aging, 2025, volume 5, pages 1669 to 1685. It is a perspective from the Aging Biomarker Consortium: it describes how they intend to build cohorts and biological-age clocks for a Chinese population. It is not a finished clock and not a clinical tool.

Sources

China · Animal study

Mechanical force, chromatin and bone in mice

Sichuan University / West China Hospital of Stomatology · 2026-01-13

Liu, Wei and colleagues, Nature Communications, 13 January 2026. In marrow cells and in mice, moderate mechanical stimulation was linked to more chromatin accessibility at FOXO1 and to changes in aged bone. Too much force was linked to DNA damage. Human cells from young and older donors were compared. This is not a treatment trial in people.

Sources

China · Scientific review

Aging biomarkers in humans and non-human primates

Aging Biomarker Consortium · 2025-09-11

A review in Nature Reviews Molecular Cell Biology, 11 September 2025, from the Aging Biomarker Consortium, with Guang-Hui Liu as corresponding author. It surveys cellular, tissue and organism markers. It does not report a trial or a treatment.

Sources

Conceptual illustration made for this site. Not a photograph of an experiment and not a figure from a paper.

Japan · Human clinical trial

iPS cells and Parkinson’s: a phase I/II trial

Kyoto University / CiRA and Kyoto University Hospital · 2025-04-16

Sawamoto and colleagues, Nature, 16 April 2025. At Kyoto University Hospital, seven patients aged 50 to 69 received dopaminergic progenitors made from allogeneic iPS cells. The trial is open-label and single-centre (jRCT2090220384). The paper discusses safety and clinical signals in that small group. It is not an approved treatment and not a longevity study.

Sources

Conceptual illustration made for this site. Not a photograph of an experiment and not a figure from a paper.

Conceptual visualization already used on this site. Not a photograph of an experiment and not a figure from a paper.

United States · Institutional news release

SenNet and a framework for senescence

National Institutes of Health

An NIH news release on the SenNet consortium, senotypes and an atlas. It calls senolytics experimental. It is an institutional release, not the paper, and not a result showing that clearing senescent cells extends human life.

Sources

Conceptual visualization already used on this site. Not a photograph of an experiment and not a figure from a paper.

Europe · Scientific review

From geroscience to precision geromedicine

Kroemer and colleagues, Cell · 2025

Kroemer and colleagues, Cell, 2025. A review of the shift from the study of aging toward what they call precision geromedicine. It does not show that human aging has been stopped or reversed.

Sources

RIKEN, The University of Osaka and the National Center for Geriatrics and Gerontology are lines to follow. No extra 2025 or 2026 paper is attached here until the source is checked.