Explorer
These are compounds from the scientific literature. They are not a sales catalog. None is presented as a way to live longer.
These are compounds from the scientific literature. They are not a sales catalog. None is presented as a way to live longer.
Promising Level B · moderate human evidence
Mitochondria
It is studied in deficiency and in some cardiac contexts. It is not a synonym for longevity.
Learn moreEstablished Level A · strong human evidence
Muscle
The performance evidence is broad. Interest in the brain and in aging is more recent and less conclusive.
Learn moreEarly research Level C · preliminary human evidence
Autophagy
There are laboratory data, observations in populations, and human trials that are still small.
Learn moreEstablished Level A · strong human evidence
Foundational nutrition
Correcting a deficit makes nutritional sense. Supplementing without a deficit is not an anti-aging strategy.
Learn morePromising Level C · preliminary human evidence
Cellular energy
NAD+ biochemistry is well described. Its decline with age, and the effect of restoring it, are studied mostly in the laboratory and in animals.
Learn moreEarly research Level C · preliminary human evidence
NAD+ precursor
Small human studies explore metabolism and insulin sensitivity. The body of evidence is still preliminary.
Learn morePromising Level C · preliminary human evidence
NAD+ precursor
Trials in adults have observed increases in blood NAD+ and acceptable short-term tolerability.
Learn moreEstablished Level A · strong human evidence
Nutrition
There is broad human evidence on triglycerides and cardiovascular health in defined contexts. That is not a label for living longer.
Learn moreEarly research Level C · preliminary human evidence
Polyphenols
The early expectation was larger than the later clinical evidence.
Learn more