Longevity Explorer

Explorer

These are compounds from the scientific literature. They are not a sales catalog. None is presented as a way to live longer.

Promising Level C · preliminary human evidence

NAD+

Cellular energy

NAD+ biochemistry is well described. Its decline with age, and the effect of restoring it, are studied mostly in the laboratory and in animals.

Promising Level C · preliminary human evidence

NAD+ precursor

Trials in adults have observed increases in blood NAD+ and acceptable short-term tolerability.

Early research Level C · preliminary human evidence

NAD+ precursor

Small human studies explore metabolism and insulin sensitivity. The body of evidence is still preliminary.

Early research Level C · preliminary human evidence

Polyphenols

The early expectation was larger than the later clinical evidence.

Promising Level B · moderate human evidence

Mitochondria

It is studied in deficiency and in some cardiac contexts. It is not a synonym for longevity.

Established Level A · strong human evidence

Nutrition

There is broad human evidence on triglycerides and cardiovascular health in defined contexts. That is not a label for living longer.

Early research Level C · preliminary human evidence

Autophagy

There are laboratory data, observations in populations, and human trials that are still small.

Established Level A · strong human evidence

Muscle

The performance evidence is broad. Interest in the brain and in aging is more recent and less conclusive.

Established Level A · strong human evidence

Foundational nutrition

Correcting a deficit makes nutritional sense. Supplementing without a deficit is not an anti-aging strategy.