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Early research Level C · preliminary human evidence

NMN

NAD+ precursor

Mechanism

Nicotinamide mononucleotide is another precursor of the same pathway.

Research summary

Small human studies explore metabolism and insulin sensitivity. The body of evidence is still preliminary.

Human evidence

It should not be presented as a proven anti-aging intervention.

Safety

This is not a treatment. Anyone who is pregnant, nursing, underage, or taking medication should consult a professional before using a supplement.

References

  1. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo EvidenceRajman L, Chwalek K, Sinclair DA. Cell Metabolism, 2018.DOI 10.1016/j.cmet.2018.02.011Reviews the role of NAD+ and of molecules that raise it. The lifespan extension it cites comes mostly from animal models.

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