Mitochondrial biology
Mitochondria make most cellular ATP and change with age. Repairing them in people remains unproven as a longevity method. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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Gene editing and CRISPR
CRISPR edits DNA sequences. A clinical use in one disease is not a license for anti-aging gene editing. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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Optogenetics
Light-sensitive tools are used in neuroscience and, in specific trials, in retinal disease. That is not evidence of a longer human life. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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Cellular senescence
Cells that stop dividing and can secrete inflammatory signals. Whether every senescent cell should be removed is not settled on this site. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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mTOR and nutrient sensing
mTOR is a nutrient-sensing pathway studied with rapamycin in models and in disease trials. This site gives no dose and no recommendation. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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CAR-T senolytic research
CAR T cells aimed at senescent cells have been reported in mice. This site does not turn that report into a human therapy. Human lifespan extension is not established here. A disease approval is not an anti-aging approval.
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2026-05-13
mTOR and rapamycin: a review that leaves the human question open
2026-04-14
A phase 1 photoswitch trial in advanced retinitis pigmentosa
2024-01-24
Senolytic CAR T cells: what a mouse study reported
Conceptual visualizations. Not photographs of experiments and not figures from papers. Evidence grades stay in the Longevity Explorer. A disease study is not an anti-aging approval. Explorer
Educational information, not medical advice. This site does not publish experimental protocols for personal use and does not recommend genetic therapies, senolytics, or experimental drugs.